Mesenchymal progenitor cells localize within hematopoietic sites throughout ontogeny
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چکیده
منابع مشابه
Mesenchymal progenitor cells localize within hematopoietic sites throughout ontogeny.
Mesenchymal stem cells (MSCs) have great clinical potential for the replacement and regeneration of diseased or damaged tissue. They are especially important in the production of the hematopoietic microenvironment, which regulates the maintenance and differentiation of hematopoietic stem cells (HSCs). In the adult, MSCs and their differentiating progeny are found predominantly in the bone marro...
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The production of interleukin 1 b (IL-1 b ) by human hematopoietic stem/progenitor cells was studied to explore the concept that these cells are not merely responders to stimuli from their microenvironment, but can themselves produce a powerful biomodulator. Cells with a CD34 1 CD45RA lo CD71 lo phenotype were purified from human umbilical cord blood and cultured one per well in serum-free medi...
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Several signaling pathways and transcription factors control the cell fate in its in vitro development and differentiation. The orchestrated use of these factors results in cell specification. In coculture methods, many of these factors secrete from host cells but control the process. Today, transcription factors required for retinal progenitor cells are well known, but the generation of these ...
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ژورنال
عنوان ژورنال: Development
سال: 2005
ISSN: 1477-9129,0950-1991
DOI: 10.1242/dev.01615